ICD-10 Code D81.6 - Major histocompatibility complex class I deficiency

ICD-10-CM Diagnosis Code D81.6

Diagnosis Code: D81.6 (Raw: D816)

Description: Major histocompatibility complex class I deficiency

Classification: International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM)

Fiscal Year: 2026

CMS Section 111 Status: Valid for reporting.

Overview & Clinical Details

ICD-10-CM code D81.6 is designated for Major histocompatibility complex class I deficiency. In medical documentation and insurance billing, this code is utilized to specify medical diagnosis for patient records, reimbursement workflows, and compliance under CMS Section 111 mandatory insurer reporting guidelines.