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ICD-10 Code F11.221 - Opioid dependence with intoxication delirium

Reviewed by Medicinsk Expert•Last updated: 2026-10-22•ICD Codes

ICD-10-CM Diagnosis Code F11.221

Diagnosis Code: F11.221 (Raw: F11221)

Description: Opioid dependence with intoxication delirium

Classification: International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM)

Fiscal Year: 2026

CMS Section 111 Status: Valid for reporting.

Overview & Clinical Details

ICD-10-CM code F11.221 is designated for Opioid dependence with intoxication delirium. In medical documentation and insurance billing, this code is utilized to specify medical diagnosis for patient records, reimbursement workflows, and compliance under CMS Section 111 mandatory insurer reporting guidelines.

Source: MedlinePlus, National Library of Medicine

MedlinePlus brings together authoritative health information from the National Library of Medicine (NLM), the National Institutes of Health (NIH), and other government agencies and health-related organizations.